abstract：:The objective of the study is to compare fatal and nonfatal cardiovascular endpoints in hypertensive patients randomised to the calcium-channel blocker, nifedipine GITS or a thiazide diuretic, co-amilozide. A total of 6592 patients from nine countries (UK, France, Israel, Spain, Italy, The Netherlands, Sweden, Denmark...

journal_title：Journal of human hypertension

authors： Brown MJ,Castaigne A,Ruilope LM,Mancia G,Rosenthal T,de Leeuw PW,Ebner F

更新日期：1996-09-01 00:00:00

abstract：:We have investigated 59 patients with mild-to-moderate uncomplicated essential hypertension in order to estimate whether salt sensitivity is associated with greater urinary albumin excretion. Patients whose average mean blood pressure (BP) value on day 5 of the high-sodium regimen (300 mmol/l NaCl) exceeded 10 mm Hg o...

journal_title：Journal of human hypertension

authors： Nesović M,Stojanović M,Nesović MM,Cirić J,Zarković M

更新日期：1996-09-01 00:00:00

abstract：:We tested the utility of qualitative microalbuminuria (MAU) screening in an office practice setting, in assessing the response of MAU to drug treatment. We enrolled general practitioners throughout Germany, who obtained histories, physical examinations, and routine laboratory values as clinically indicated on > 6000 n...

journal_title：Journal of human hypertension

authors： Agrawal B,Wolf K,Berger A,Luft FC

更新日期：1996-08-01 00:00:00

abstract：:The contribution of hypertension to adult mortality in Africa has not been well studied. Although cross-sectional surveys have provided data on the prevalence of this condition, the relative risk of death associated with hypertension has not been defined. In the face of high levels of competing mortality from infectio...

journal_title：Journal of human hypertension

authors： Kaufman JS,Rotimi CN,Brieger WR,Oladokum MA,Kadiri S,Osotimehin BO,Cooper RS

更新日期：1996-07-01 00:00:00

abstract：:The aim of this study is to investigate how the blood pressure (BP) circadian rhythm (CR) is influenced by life style. Two groups of subjects were recruited from Nepal and Japan because of the extremely different occupational routines of these countries. The Nepalese represent a rural culture, while the Japanese refle...

journal_title：Journal of human hypertension

authors： Kawasaki T,Cugini P,Itoh K,Uezono K,Ogaki T,Yoshimizu Y,Cornélissen G

更新日期：1996-05-01 00:00:00

abstract：OBJECTIVE:The European Arteriosclerosis Study (EARS) was designed to identify variables which discriminate subjects with a paternal history of premature coronary heart disease (CHD) from controls and to study the distribution of these variables across Europe. In this article we report on the blood pressure (BP) data. ...

journal_title：Journal of human hypertension

authors： Masana L,Farinaro E,De Henauw S,Nicaud V

更新日期：1996-04-01 00:00:00

abstract：:Hypertension has been associated with hyperinsulinemia and insulin resistance. The elevations in plasma insulin are the apparent adaptation of the pancreatic beta cell to the resistance to insulin. Maintenance of normal insulin release is therefore of great importance for subjects with hypertension. The potassium chan...

journal_title：Journal of human hypertension

authors： Ligtenberg JJ,Leenaers AD,Van Haeften TW,Smit AJ,Sluiter WJ,Reitsma WD

更新日期：1996-04-01 00:00:00

abstract：:Professional historians generally treat the phrase 'what if' with pardonable scorn. It is a speculation which necessarily will never be tested in the real world. Nevertheless, there is a reasonable likelihood that, if typhoid fever had not carried off Frederick Akbar Mahomed at the age of 35, clinical research in Brit...

journal_title：Journal of human hypertension

authors： Swales JD

更新日期：1996-03-01 00:00:00

abstract：:The increased viscosity of blood of hypertensive patients can be assumed to be a risk factor for the development of cardiovascular diseases. The aim of the present study was to elucidate whether anti-hypertensive treatment has any impact on blood rheology. Twenty patients with previously untreated hypertension who con...

journal_title：Journal of human hypertension

authors： Linde T,Sandhagen B,Hägg A,Mörlin C,Danielson BG

更新日期：1996-03-01 00:00:00

abstract：:Results of an analysis of the cost-effectiveness of hypertension treatment in Sweden are presented. The cost per life-year gained decreases with age for both men and women and is relatively low for middle-aged and older men and women even in the blood pressure range 90-94 mmHg. The results indicate that it is in gener...

journal_title：Journal of human hypertension

authors： Johannesson M

更新日期：1996-02-01 00:00:00

abstract：:The National Blood Pressure Programme in Germany (NBP) was established in 1985. The NBP is committed to a process of programme development and implementation that incorporates public health relevance, recent research results, and attempts of scientific module evaluation. Among selected examples of successful modules, ...

journal_title：Journal of human hypertension

authors： Hense HW

更新日期：1996-02-01 00:00:00

abstract：:This paper addresses approaches to evaluating the importance of different childhood behaviours on subsequent risk of high blood pressure and related cardiovascular risk factors and outlines results of a randomised controlled trial of nutrition and exercise interventions in schoolchildren. Clustering of cardiovascular ...

journal_title：Journal of human hypertension

authors： Beilin L,Burke V,Milligan R

更新日期：1996-02-01 00:00:00

abstract：:Syst. China Trial aimed to determine whether titrated antihypertensive treatment could reduce the risk of stroke incidence and other cardiovascular complications among 2,298 older Chinese patients (> or = 60) with isolated systolic hypertension. The data from 3 years follow-up showed that the blood pressure reduction ...

journal_title：Journal of human hypertension

authors： Lisheng L

更新日期：1996-02-01 00:00:00

abstract：:The aim of this study was to evaluate the prevalence of renal artery stenosis in patients with clinical signs of peripheral vascular disease and hypertension. One hundred patients, mean age 69 years (range 45-88) with symptoms and clinical signs of severe peripheral ischemia, underwent aortography to determine the deg...

journal_title：Journal of human hypertension

authors： Wachtell K,Ibsen H,Olsen MH,Laybourn C,Christoffersen JK,Nørgaard H,Mantoni M,Lund JO

更新日期：1996-02-01 00:00:00

abstract：:In phaeochromocytoma, sudden hypertensive or arrhythmic episodes are believed to be associated with excessive free catecholamine excretion. However, lack of correlation between blood pressure (BP) and plasma catecholamine levels has been reported. Therefore an attempt was made to assess the sympathovagal balance befor...

journal_title：Journal of human hypertension

authors： Dabrowska B,Dabrowski A,Pruszczyk P,Skrobowski A,Wocial B

更新日期：1996-01-01 00:00:00

abstract：:A sodium intervention project was carried out in Tianjin, China, as part of the Tianjin Project, which is a national pilot, community-based intervention programme to reduce non-communicable diseases. The aim of this 3 year sodium project was to evaluate the feasibility and effects of sodium reduction in the population...

journal_title：Journal of human hypertension

authors： Tian HG,Guo ZY,Hu G,Yu SJ,Sun W,Pietinen P,Nissinen A

更新日期：1995-12-01 00:00:00

abstract：:Endothelin-1 (ET-1) is a potent vasoconstrictor peptide derived from endothelium. The presence of ET-1 in human vascular endothelium and in the plasma suggests that it may play a role in the regulation of vascular tone and blood pressure (BP) in humans. The aim of this study was to evaluate the behaviour of plasma ET-...

journal_title：Journal of human hypertension

authors： Letizia C,Cerci S,De Ciocchis A,D'Ambrosio C,Scuro L,Scavo D

更新日期：1995-11-01 00:00:00

abstract：:Activation of the renin-angiotensin system both systemically and locally seems to be of importance for cardiovascular hypertrophy and remodelling. The octapeptide angiotensin II definitively plays a central role. In the reversal, for example, of left ventricular hypertrophy, so far the most important independent risk ...

journal_title：Journal of human hypertension

authors： Dahlöf B

更新日期：1995-11-01 00:00:00

abstract：:A random sample of 200 East Anglian general practitioners was surveyed to establish current trends in the management of hypertension, including measurement of blood pressure (BP), patient investigation, treatment and follow-up. A total of 125 (62.5%) completed questionnaires was returned. Responses were used to assess...

journal_title：Journal of human hypertension

authors： Dickerson JE,Garratt CJ,Brown MJ

更新日期：1995-10-01 00:00:00

abstract：:The influence of high density lipoproteins (HDL) on platelet function were examined in vivo and in vitro. Intraplatelet, ionised calcium concentrations ([Ca2+]i) were measured using the fluorescent dye Quin-2. In vitro, platelet responses to AVP were measured in the presence or absence of HDL. Pre-treating platelets f...

journal_title：Journal of human hypertension

authors： Graham D,Simpson HD,Dominiczak AF,Caslake M,Davies DL,Kenyon CJ

更新日期：1995-09-01 00:00:00

abstract：:Genetic influences in cerebrovascular disease (CVD) may act either independently or by predisposing to, or modulating, the effect of risk factors such as hypertension. Factors involved in the pathogenesis of atherosclerosis, thrombosis and vasoconstriction are important in CVD. The angiotensinogen gene has recently be...

journal_title：Journal of human hypertension

authors： Barley J,Markus H,Brown M,Carter N

更新日期：1995-08-01 00:00:00

abstract：:For the epidemiologist, the development of any new therapy or strategy must respond to the following three questions: does a need exist? Is there a new way of meeting that need? Can a valid assessment be made of the efficacy of the new therapy? New antihypertensive treatments or strategies are needed, even in 1994: in...

journal_title：Journal of human hypertension

authors： Chatellier G

更新日期：1995-08-01 00:00:00

abstract：:The aim of the present paper was to evaluate the influence of a family history of hypertension and the degree of obesity as indicated by tertiles of body mass index on ambulatory blood pressure (BP) values in large number (n = 406) of young mild essential hypertensives. Positive family history of hypertension was asso...

journal_title：Journal of human hypertension

authors： Narkiewicz K,Gatti P,Garavelli G,Pegoraro F,Milani L,Gelisio R,Palatini P

更新日期：1995-07-01 00:00:00

abstract：:A study was undertaken in 298 normotensive, normolipidaemic and normoglycaemic subjects to define the range of erythrocyte sodium-lithium countertransport activity in this cohort and to determine the associations between countertransport activity and markers of vascular risk. Countertransport activity showed a positiv...

journal_title：Journal of human hypertension

authors： Hardman TC,Dubrey SW,Soni S,Lant AF

更新日期：1995-07-01 00:00:00

abstract：:Evidence from the medical literature is reviewed to indicate that ambulatory monitoring of blood pressure (ABPM) is a better predictor of target organ damage and clinical outcome in the hypertensive patient than clinic measurements of blood pressure (BP). A re-analysis of the documented BPs from the placebo limb of th...

journal_title：Journal of human hypertension

authors： Padfield PL,Benediktsson R

更新日期：1995-06-01 00:00:00

abstract：:The media of most blood vessels is occupied by vascular smooth muscle cells. In areas they may be replaced by glomus cells, pericytes or renin-secreting myoepithelioid cells. These cells may be regarded as phenotypic variants of vascular smooth muscle cells. In disease, ordinary vascular smooth muscle cells may also a...

journal_title：Journal of human hypertension

authors： Lindop GB,Boyle JJ,McEwan P,Kenyon CJ

更新日期：1995-06-01 00:00:00

abstract：:The study objective was to compare blood pressure (BP) measurement by the Hawksley random-zero sphygmomanometer and the standard mercury sphygmomanometer. Comparison of simultaneous 'blind' BP measurements were made using the Hawksley random-zero sphygmomanometer and the standard mercury sphygmomanometer linked by a Y...

journal_title：Journal of human hypertension

authors： Mackie A,Whincup P,McKinnon M

更新日期：1995-05-01 00:00:00

abstract：:We compared haemodynamic and humoral responses to nifedipine and nilvadipine in 25 elderly hypertensives. The study had a single-blind crossover design. Doppler flowmetry and laboratory examinations were performed before and after nifedipine and nilvadipine. Both nifedipine and nilvadipine significantly reduced mean a...

journal_title：Journal of human hypertension

authors： Shimamoto H,Shimamoto Y

更新日期：1995-04-01 00:00:00

abstract：:The interactions of intrarenal dopamine (DA) synthesis and natriuresis were studied in 11 healthy volunteers by giving a low and high sodium diet (LoSo, 50 mmol Na+; HiSo, 250 mmol Na+). On 2 days in both dietary phases an acute saline load was given, without or with an infusion of the DA precursor 3, 4-dihydroxypheny...

journal_title：Journal of human hypertension

authors： Barendregt JN,Muizert Y,van Nispen tot Pannerden LL,Chang PC

更新日期：1995-03-01 00:00:00

abstract：:The anti-hypertensive efficacy and safety of extended-release (ER) felodipine (5, 10 or 20 mg) and amlodipine (5 or 10 mg) once daily were compared in patients with mild to moderate essential hypertension in a double-blind, double-dummy, randomised, comparative study. One hundred and eighteen patients were randomised ...

journal_title：Journal of human hypertension

authors： Høegholm A,Wiinberg N,Rasmussen E,Nielsen PE

更新日期：1995-03-01 00:00:00

abstract：:The presence of hepatic steatosis was determined in 180 middle-aged male workers by ultrasonography and was found in 39 (22%) of them. Body mass index (BMI), systolic and diastolic blood pressure (BP) and serum levels of asparate aminotransferase (AST), alanine aminotransferase (ALT) and gamma-glutamyl transpeptidase ...

journal_title：Journal of human hypertension

authors： Ikai E,Ishizaki M,Suzuki Y,Ishida M,Noborizaka Y,Yamada Y

更新日期：1995-02-01 00:00:00

abstract：:There is a strong association between cigarette smoking and accelerated hypertension. In mild hypertension smoking cigarettes has a distinct pressor effect and caffeine a small but more prolonged pressor action. Coffee and cigarette smoking together have an additive effect on blood pressure (BP). We have examined the ...

journal_title：Journal of human hypertension

authors： Freestone S,Yeo WW,Ramsay LE

更新日期：1995-02-01 00:00:00

abstract：:The World Hypertension League (WHL) International Art Competition started in 1991. The idea was to raise public awareness regarding hypertension prevention and treatment through unconventional means: Art. The purpose of this paper is to summarise the experience the WHL gained during preparation and follow-up activitie...

journal_title：Journal of human hypertension

authors： Pötzsch J

更新日期：1995-01-01 00:00:00

abstract：:The interaction between doctors and their hypertensive patients still suffers from a number of shortcomings owing to ignorance and misconceptions on both sides as well as poorly defined mutual goals. In this paper, an attempt is made to define common goals of doctors and patients and to describe the information status...

journal_title：Journal of human hypertension

authors： Unger T

更新日期：1995-01-01 00:00:00

abstract：:This is the first report of long-term use (one year) of isradipine, a new dihydropyridine calcium channel blocker, in the treatment of elderly patients with essential hypertension. Patients completing a three month, double-blind, multicentre study comparing isradipine to hydrochlorothiazide (HCTZ) were eligible to enr...

journal_title：Journal of human hypertension

authors： Stein GH,Hamilton BP,Hamilton JH,Holtzman JL,Kirkendall WM,Abrams A,Neri G,Culter R,Matthews K

更新日期：1994-12-01 00:00:00

abstract：:The aims of this study were to determine: (1) the proportion of elderly hypertensive subjects currently attending a hospital hypertension clinic suitable for a trial of antihypertensive drug withdrawal, (2) the proportion of suitable patients who can be successfully withdrawn from drug therapy while receiving nonpharm...

journal_title：Journal of human hypertension

authors： Fotherby MD,Potter JF

更新日期：1994-11-01 00:00:00

abstract：:The purpose of this work was to assess the best haemodynamic determinant of left ventricular hypertrophy (LVH) in patients with essential hypertension. We studied the relationships between left ventricular mass (LVM) and casual, exercise and 24h ambulatory blood pressure monitoring (ABPM) in 60 newly discovered patien...

journal_title：Journal of human hypertension

authors： Grossman E,Alster Y,Shemesh J,Nussinovitch N,Rosenthal T

更新日期：1994-10-01 00:00:00

abstract：:While the arterial tree is exposed to increased pressure flow, paradoxically the complications of hypertension are mainly thrombotic rather than haemorrhage. Improved techniques have allowed the identification of haemorrheological indices, coagulation factors and markers of arteriolar endothelial and platelet dysfunct...

journal_title：Journal of human hypertension

authors： Lip GY,Beevers DG

更新日期：1994-09-01 00:00:00

abstract：:Mild to moderate hypertension is usually asymptomatic and therefore the impact on quality of life and side-effects of the antihypertensive treatment can have a negative effect on treatment compliance. A number of comparative studies have addressed quality of life issues with various antihypertensive agents, and the re...

journal_title：Journal of human hypertension

authors： Os I

更新日期：1994-09-01 00:00:00

abstract：:This study evaluated insulin secretion and insulin sensitivity before and after short-term oral administration of doxazosin in patients with essential hypertension. The hypertensive group consisted of 11 nonobese subjects (aged 41.0 +/- 2.5 years (mean +/- SEM), body mass index 24.0 +/- 0.53 kg/m2). The normotensive g...

journal_title：Journal of human hypertension

authors： Yamasaki Y,Shiba Y,Sekiya M,Tsujino T,Hakui N,Kawamori R,Kamada T

更新日期：1994-08-01 00:00:00